Redox mechanisms in age-related lung fibrosis

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Redox mechanisms in age-related lung fibrosis

Redox signaling and oxidative stress are associated with tissue fibrosis and aging. Aging is recognized as a major risk factor for fibrotic diseases involving multiple organ systems, including that of the lung. A number of oxidant generating enzymes are upregulated while antioxidant defenses are deficient with aging and cellular senescence, leading to redox imbalance and oxidative stress. Howev...

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ژورنال

عنوان ژورنال: Redox Biology

سال: 2016

ISSN: 2213-2317

DOI: 10.1016/j.redox.2016.06.005